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PM534

Product Specifications

CAS Number

2446376-25-4

Target

Microtubule Associated

Related Pathways

Cytoskeletal Signaling

Bioactivity

PM534, a tubulin-targeting agent, inhibits tubulin assembly with IC50 values of 0.8-3.2 nM. PM534 binds to the colchicine site of tubulin, demonstrating high antitumor activity [1].

Smiles

[C@@H](NC(=O)[C@@]1(C)N=C(\C(=N\O)\C)SC1)(CCC)C2=CC(OCC3CC3)=CC(=O)O2

Molecular Formula

C20H27N3O5S

Molecular Weight

421.51

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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