PLK1/BRD4-IN-2
Product Specifications
CAS Number
2251709-89-2
Target
Epigenetic Reader Domain
Related Pathways
Chromatin/Epigenetic
Bioactivity
PLK1/BRD4-IN-2 (compound 15), an analog of BI-2536, simultaneously inhibits both Polo-like kinase 1 (PLK1 IC 50 = 40 nM) and BRD4 bromodomain (BRD4-BD1 IC 50 = 28 nM) as a dual inhibitor [1].
Smiles
C[C@H]1N(C=2C(N(C)C1=O)=CN=C(NC3=C(OC)C=C(C(=O)N4CCCCCC4)C=C3)N2)C5CCCC5
Molecular Formula
C27H36N6O3
Molecular Weight
492.61
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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