Pim-1 kinase inhibitor 10
Product Specifications
CAS Number
2918764-57-3
Target
Caspase, Apoptosis, Pim
Related Pathways
Apoptosis, JAK/STAT signaling, Proteases/Proteasome, Chromatin/Epigenetic
Bioactivity
Pim-1 Kinase Inhibitor 10 (compound 13a) acts as both a competitive and non-competitive inhibitor of PIM-1/2 kinase, promoting cell apoptosis and displaying anticancer properties. Additionally, this compound triggers the activation of caspase 3/7 [1].
Smiles
C(#N)C1=C(C=C(NC1=O)C2=CC(O)=CC=C2)C3=CC=4C(NC3=O)=CC=CC4
Molecular Formula
C21H13N3O3
Molecular Weight
355.35
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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