Pim-1 kinase inhibitor 10
Product Specifications
CAS Number
2918764-57-3
Target
Caspase|||Apoptosis|||Pim
Related Pathways
Apoptosis|||JAK/STAT signaling|||Proteases/Proteasome|||Chromatin/Epigenetic
Bioactivity
Pim-1 Kinase Inhibitor 10 (compound 13a) acts as both a competitive and non-competitive inhibitor of PIM-1/2 kinase, promoting cell apoptosis and displaying anticancer properties. Additionally, this compound triggers the activation of caspase 3/7 [1].
Smiles
C(#N)C1=C(C=C(NC1=O)C2=CC(O)=CC=C2)C3=CC=4C(NC3=O)=CC=CC4
Molecular Formula
C21H13N3O3
Molecular Weight
355.35
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
038771-HRP 200 µL
MYT1, NT (MYT1, KIAA0835, KIAA1050, MTF1, MYTI, PLPB1, Myelin transcription factor 1, Myelin transcription factor I, Proteolipid protein-binding protein) (Azide free) (HRP) discontinued
Sign In for Pricing
View Details abx067989-01 10 µg
Human Membrane Cofactor Protein (MCP / CD46) Protein
Sign In for Pricing
View Details abx067989-02 50 µg
Human Membrane Cofactor Protein (MCP / CD46) Protein
Sign In for Pricing
View Details abx067989-03 100 µg
Human Membrane Cofactor Protein (MCP / CD46) Protein
Sign In for Pricing
View Details