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PI3Kα-IN-16

Product Specifications

CAS Number

1448711-61-2

Target

PI3K, Wnt/beta-catenin

Related Pathways

PI3K/Akt/mTOR signaling, Stem Cells, Cytoskeletal Signaling

Bioactivity

PI3Kα-IN-16 (Z86) is a recently developed inhibitor of PI3Kα, displaying an IC 50 of 4.28 μM. With potent efficacy, it inhibits the growth and migration of CRCs mediated by PI3K. Additionally, PI3Kα-IN-16 also suppresses the Wnt signaling pathway [1].

Smiles

C(C)N1C=2C(C=3C1=CC=CC3)=CC(C(OC(C)C)=O)=NC2C=4C5=C(C=CC4)C=CC=C5

Molecular Formula

C27H24N2O2

Molecular Weight

408.49

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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