PI3Kα-IN-16
Product Specifications
CAS Number
1448711-61-2
Target
PI3K, Wnt/beta-catenin
Related Pathways
PI3K/Akt/mTOR signaling, Stem Cells, Cytoskeletal Signaling
Bioactivity
PI3Kα-IN-16 (Z86) is a recently developed inhibitor of PI3Kα, displaying an IC 50 of 4.28 μM. With potent efficacy, it inhibits the growth and migration of CRCs mediated by PI3K. Additionally, PI3Kα-IN-16 also suppresses the Wnt signaling pathway [1].
Smiles
C(C)N1C=2C(C=3C1=CC=CC3)=CC(C(OC(C)C)=O)=NC2C=4C5=C(C=CC4)C=CC=C5
Molecular Formula
C27H24N2O2
Molecular Weight
408.49
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
132245-ML750 100 µL
RABL6 (C9orf86, Rab-like Protein 6, GTP-binding Protein Parf, Partner of ARF, Rab-like Protein 1, RBEL1, C9orf86, PARF, FLJ10101, FLJ13045) (MaxLight 750) discontinued
Sign In for Pricing
View Details 