PI3Kα-IN-1

2100855-80-7

PI3K

PI3K/Akt/mTOR signaling

PI3Kα-IN-1 is an inhibitor specifically targeting PI3Kα with an IC50 of less than 0.5 nM, and it also inhibits mTOR with an IC50 of 104 nM [1].

N(C(NC1=CC=C(NC(C)=O)C=C1)=O)C2=CC=C(C=3N=C(C4=C(N3)C=CC=N4)N5CCOCC5)C=C2

C26H25N7O3

483.52

Ice Packs

-20°C