P-gp inhibitor 14
Product Specifications
CAS Number
2892571-47-8
Target
P-gp
Related Pathways
Membrane transporter/Ion channel|||Neuroscience
Bioactivity
Compound 8a, also known as P-gp inhibitor 14, demonstrates high affinity as a P-gp inhibitor and effectively reverses P-gp-mediated multidrug resistance (EC 50 = 48.74 nM) . Additionally, this compound exhibits a weak inhibitory effect on CYP3A4 activity [1].
Smiles
O(C)C=1C2=C(C=3C=4C5=C(C(OC)=CC4CN(CC3C1)C6=CC=C(CCN7CC=8C(CC7)=CC(OC)=C(OC)C8)C=C6)OCO5)OCO2
Molecular Formula
C37H38N2O8
Molecular Weight
638.71
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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