PAT1inh-A0030
Product Specifications
CAS Number
1030097-65-4
Target
Chloride channel, Others
Related Pathways
Membrane transporter/Ion channel, Others
Bioactivity
PAT1inh-A0030 is a selective inhibitor of PAT1 (SLC26A6) with an IC 50 value of 1.0 μM. It inhibits fluid absorption in the ileum of wild-type and cystic fibrosis (CF) mice (CftrdelF508/delF508) in a closed-loop model of intestinal fluid absorption and can be used in the study of intestinal diseases related to CF [1].
Smiles
N(CC1=CC=CC=C1)(C)C2=C3C(=NC(C(OCC)=O)=N2)ON=C3C
Molecular Formula
C17H18N4O3
Molecular Weight
326.35
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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