Pan-KRAS-IN-5
Product Specifications
CAS Number
3027172-23-9
Target
Kras, Apoptosis, Ras
Related Pathways
Apoptosis, MAPK, GPCR/G Protein
Bioactivity
Pan-KRAS-IN-5 (compound 15a) is a pan-KRAS translation inhibitor targeting 5′-UTR RNA G-quadruplexes (rG4s) . It induces cell cycle arrest and promotes apoptosis in KRAS-driven cancer cells [1].
Smiles
C[N+]=1C2=C(C=C(F)C(NCCN3CCCC3)=C2)C=CC1/C=C/C4=CC=5C(OC4=O)=CC(N(CC)CC)=CC5.[I-]
Molecular Formula
C31H36FIN4O2
Molecular Weight
642.55
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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