PAN endonuclease-IN-1
Product Specifications
CAS Number
2378640-67-4
Target
Influenza Virus
Related Pathways
Microbiology/Virology
Bioactivity
Compound 23, also known as PAN endonuclease-IN-1, demonstrates potent inhibitory activity against PAN endonuclease, a vital element of the influenza virus replication machinery and a significant antiviral target [1]. It exhibits dissociation constants (Kd) of 277 ?M, 384 ?M, and 328 ?M for the wild type (WT), I38T, and E23K variants of PAN endonuclease respectively.
Smiles
C(F)(F)(F)C1=C(C=CC(=C1)C=2NN=NN2)C=3NC(C(O)=O)=C(O)C(=O)C3
Molecular Formula
C14H8F3N5O4
Molecular Weight
367.24
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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