OSM-S-106
Product Specifications
CAS Number
2650846-59-4
Target
Parasite
Related Pathways
Microbiology/Virology
Bioactivity
OSM-S-106 is a pro-inhibitor that inhibits PfAsnRS through enzyme-mediated production of an Asn-OSM-S-106 adduct, inhibits protein translation, and activates the amino acid starvation response. OSM-S-106 exhibits selective activity against Plasmodium blood and liver stages and shows low intrinsic clearance by human microsomes [1].
Smiles
S(N)(=O)(=O)C=1C=C(C=2SC=3C(C2)=NC=NC3N)C=CC1
Molecular Formula
C12H10N4O2S2
Molecular Weight
306.36
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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