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OSM-S-106

Product Specifications

CAS Number

2650846-59-4

Target

Parasite

Related Pathways

Microbiology/Virology

Bioactivity

OSM-S-106 is a pro-inhibitor that inhibits PfAsnRS through enzyme-mediated production of an Asn-OSM-S-106 adduct, inhibits protein translation, and activates the amino acid starvation response. OSM-S-106 exhibits selective activity against Plasmodium blood and liver stages and shows low intrinsic clearance by human microsomes [1].

Smiles

S(N)(=O)(=O)C=1C=C(C=2SC=3C(C2)=NC=NC3N)C=CC1

Molecular Formula

C12H10N4O2S2

Molecular Weight

306.36

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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