ORIC-533
Product Specifications
CAS Number
2641306-62-7
Target
CD73
Related Pathways
Immunology/Inflammation
Bioactivity
ORIC-533 is a selective CD73 inhibitor that is orally active and competes with AMP. It revitalizes the proliferation and activation of immunosuppressed CD8+ T cells and induces notable lysis and cell death in multiple myeloma cells within the bone marrow microenvironment [1].
Smiles
O[C@H]1[C@H](N2C=3C(C=N2)=C(NC4CCCC4)N=C(Cl)N3)O[C@H](CO[C@](COCC=5NN=NN5)(P(=O)(O)O)CO)[C@H]1O
Molecular Formula
C20H29ClN9O9P
Molecular Weight
605.93
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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