NST-628
Product Specifications
CAS Number
3002056-30-3
Target
Raf, Molecular Glues, MEK
Related Pathways
PROTAC, MAPK
Purity
0.9862
Bioactivity
NST-628 is a pan-RAF-MEK molecular glue that prevents RAF from phosphorylating and activating MEK, inhibiting the RAF-MEK signaling complex.
Smiles
O=C1OC=2C=C(OC3=NC=CC=C3F)C=CC2C(=C1CC=4C=CN=C(NS(=O)(=O)NC)C4F)C
Molecular Formula
C22H18F2N4O5S
Molecular Weight
488.46
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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