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NST-628

Product Specifications

CAS Number

3002056-30-3

Target

Raf|||Molecular Glues|||MEK

Related Pathways

PROTAC|||MAPK

Purity

0.9862

Bioactivity

NST-628 is a pan-RAF-MEK molecular glue that prevents RAF from phosphorylating and activating MEK, inhibiting the RAF-MEK signaling complex.

Smiles

O=C1OC=2C=C(OC3=NC=CC=C3F)C=CC2C(=C1CC=4C=CN=C(NS(=O)(=O)NC)C4F)C

Molecular Formula

C22H18F2N4O5S

Molecular Weight

488.46

Shipping Conditions

Cool pack

Storage Temperature

-20°C

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