NSC727447
Product Specifications
CAS Number
40106-12-5
Target
HIV Protease, DNA/RNA Synthesis
Related Pathways
Microbiology/Virology, Proteases/Proteasome, DNA Damage/DNA Repair, Cell Cycle/Checkpoint
Bioactivity
NSC727447 is an inhibitor targeting ribonuclease H (Rnase H) in both HIV-1 and HIV-2. It exhibits minimal activity against E. coli RNase H, demonstrating significant selectivity for human Rnase H with IC50 values of 2.0 μM, 2.5 μM, 100 μM, and 10.6 μM, respectively [1].
Smiles
C(N)(=O)C=1C2=C(SC1N)CCCCC2
Molecular Formula
C10H14N2OS
Molecular Weight
210.3
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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