Nrf2 degrader 1

Product Specifications

CAS Number

3025286-00-1

Target

Nrf2|||PROTACs

Related Pathways

PROTAC|||Immunology/Inflammation

Bioactivity

Nrf2 degrader 1 (compound 1), a PROTAC Nrf2 degrader, exhibits anticancer properties by inhibiting the growth of cancer cells. It demonstrates IC 50 values of 100 nM for A549 cells and 40 nM for LK-2 cells, indicating potent efficacy [1].

Smiles

O=C1C=2C(C(=O)N1C3C(=O)NC(=O)CC3)=CC=CC2NCCOCCOC4=CC(CC(NC5=NC(=C(C)S5)C=6C=C7C(=CC6)N(C(=O)C8=C(C)C=CC=C8)CC7)=O)=CC=C4

Molecular Formula

C45H42N6O8S

Molecular Weight

826.92

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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