NPD10084
Product Specifications
CAS Number
1040706-91-9
Target
PKM
Related Pathways
Metabolism
Bioactivity
NPD10084 is an inhibitor of pyruvate kinase PKM2 that blocks non-glycolytic signaling in cancer cells by disrupting PKM2's interaction with ?-catenin or STAT3, thus inhibiting downstream pathways. It demonstrates antiproliferative effects against colorectal cancer cells both in vitro and in vivo [1].
Smiles
C(=O)(N1CC=2C=3C(NC2CC1)=CC=CC3)C4=CC=5C(N4)=CC=CC5OC
Molecular Formula
C21H19N3O2
Molecular Weight
345.39
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS1449929-01 0.02 mg (E-Coli)
Recombinant Neisseria meningitidis serogroup B Cell division protein FtsA (ftsA)
Ask
View Details MBS1449929-02 0.02 mg (Yeast)
Recombinant Neisseria meningitidis serogroup B Cell division protein FtsA (ftsA)
Ask
View Details 
MBS1449929-03 0.1 mg (E-Coli)
Recombinant Neisseria meningitidis serogroup B Cell division protein FtsA (ftsA)
Ask
View Details MBS1449929-04 0.1 mg (Yeast)
Recombinant Neisseria meningitidis serogroup B Cell division protein FtsA (ftsA)
Ask
View Details MBS1449929-05 0.02 mg (Baculovirus)
Recombinant Neisseria meningitidis serogroup B Cell division protein FtsA (ftsA)
Ask
View Details 
MBS1449929-06 0.02 mg (Mammalian-Cell)
Recombinant Neisseria meningitidis serogroup B Cell division protein FtsA (ftsA)
Ask
View Details