NNRT-IN-2
Product Specifications
CAS Number
2999794-78-2
Target
HIV Protease, Reverse Transcriptase
Related Pathways
Proteases/Proteasome, Microbiology/Virology
Bioactivity
NNRT-IN-2 (compound 7w) is an orally administered non-nucleoside reverse transcriptase inhibitor (NNRTI) that effectively suppresses both wild-type HIV-1 and various mutant strains. It inhibits HIV-1 reverse transcriptase with an EC 50 value of 22 nM. Additionally, NNRT-IN-2 exhibits insensitivity to CYP and hERG, demonstrating favorable safety and pharmacokinetic profiles [1].
Smiles
O(C1=C(C(F)(F)F)C=CN(CC=2N(C)C(=O)NN2)C1=O)C=3C4=C(C=CC3)C=NC=C4
Molecular Formula
C19H14F3N5O3
Molecular Weight
417.34
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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