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NLRP3-IN-37

Product Specifications

CAS Number

3033054-51-9

Target

NOD-like Receptor (NLR)

Related Pathways

Immunology/Inflammation

Bioactivity

NLRP3-IN-37 (Compound 23), an NLRP3 inhibitor (EC50: 5 nM), can be used for research on NLRP3-related conditions, including gout, pseudogout, CAPS, NASH fibrosis, heart failure, idiopathic pericarditis, atopic dermatitis, inflammatory bowel disease, Alzheimer's Disease, Parkinson's Disease, and traumatic brain injury [1].

Smiles

CN1C[C@@]2(N(C=3C4=C(C(=NN3)C5=C(O)C=C(C(F)(F)F)C=C5)C=CC=N4)CC[C@@]2(CC1)[H])[H]

Molecular Formula

C22H22F3N5O

Molecular Weight

429.44

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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