NLRP3-IN-37
Product Specifications
CAS Number
3033054-51-9
Target
NOD-like Receptor (NLR)
Related Pathways
Immunology/Inflammation
Bioactivity
NLRP3-IN-37 (Compound 23), an NLRP3 inhibitor (EC50: 5 nM), can be used for research on NLRP3-related conditions, including gout, pseudogout, CAPS, NASH fibrosis, heart failure, idiopathic pericarditis, atopic dermatitis, inflammatory bowel disease, Alzheimer's Disease, Parkinson's Disease, and traumatic brain injury [1].
Smiles
CN1C[C@@]2(N(C=3C4=C(C(=NN3)C5=C(O)C=C(C(F)(F)F)C=C5)C=CC=N4)CC[C@@]2(CC1)[H])[H]
Molecular Formula
C22H22F3N5O
Molecular Weight
429.44
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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