NLRP3-IN-28
Product Specifications
CAS Number
2922814-80-8
Target
NOD-like Receptor (NLR), Pyroptosis
Related Pathways
Apoptosis, Immunology/Inflammation
Bioactivity
NLRP3-IN-28 (compound N77) serves as a potent inhibitor of NLRP3, effectively blocking Nigericin-induced pyroptosis with an EC50 of 0.07μM. Additionally, it mitigates inflammatory reactions in vivo [1].
Smiles
OC1=C(C2=CC=C(S(C)(=O)=O)N=N2)C=CC(C(F)(F)F)=C1
Molecular Formula
C12H9F3N2O3S
Molecular Weight
318.27
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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