Nitracrine dihydrochloride hydrate
Product Specifications
CAS Number
55429-45-3
Target
DNA/RNA Synthesis
Related Pathways
DNA Damage/DNA Repair, Cell Cycle/Checkpoint
Bioactivity
Nitracrine (dihydrochloride hydrate), a 1-nitroacridine derivative, inhibits RNA synthesis, reversibly binds to DNA, and forms covalent adducts with DNA in vivo. It is a potent hypoxia-selective and antitumor agent in vitro, exhibiting cytotoxicity towards most cells [1] [2] [3].
Smiles
CN(C)CCCNC1=C(C=CC=C2)C2=NC3=C1C([N+]([O-])=O)=CC=C3.Cl.O.Cl
Molecular Formula
C18H24Cl2N4O3
Molecular Weight
415.31
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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