NAMPT activator-6
Product Specifications
CAS Number
2237267-86-4
Target
NAMPT
Related Pathways
Metabolism
Bioactivity
NAMPT activator-6, a regulatory molecule for the optical control system of NAMPT and NAD+, can be used to design efficient photoswitchable proteolysis-targeting chimeras (PS-PROTACs) for light-dependent, reversible regulation of NAMPT and NAD+, thereby reducing toxicity associated with inhibitor-based PS-PROTACs. This enables antitumor activity and in vivo modulation of NAMPT and NAD+ through optical manipulation [1].
Smiles
S(=O)(=O)(C1=CC=C(NC(NCC=2C=CN=CC2)=O)C=C1)N3CCNCC3
Molecular Formula
C17H21N5O3S
Molecular Weight
375.45
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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