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NAMPT activator-6

Product Specifications

CAS Number

2237267-86-4

Target

NAMPT

Related Pathways

Metabolism

Bioactivity

NAMPT activator-6, a regulatory molecule for the optical control system of NAMPT and NAD+, can be used to design efficient photoswitchable proteolysis-targeting chimeras (PS-PROTACs) for light-dependent, reversible regulation of NAMPT and NAD+, thereby reducing toxicity associated with inhibitor-based PS-PROTACs. This enables antitumor activity and in vivo modulation of NAMPT and NAD+ through optical manipulation [1].

Smiles

S(=O)(=O)(C1=CC=C(NC(NCC=2C=CN=CC2)=O)C=C1)N3CCNCC3

Molecular Formula

C17H21N5O3S

Molecular Weight

375.45

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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