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MK-8527

Product Specifications

CAS Number

1810869-23-8

Target

Reverse Transcriptase, HIV Protease, Antiviral

Related Pathways

Microbiology/Virology, Immunology/Inflammation, Proteases/Proteasome

Purity

0.9915

Bioactivity

MK-8527 is an orally active HIV-1 inhibitor and nucleoside reverse transcriptase translocation inhibitor with an IC50 of 0.21 nM. It is phosphorylated intracellularly to its active triphosphate form, exhibiting antiviral activity.

Smiles

NC1=C2C(N(C=C2)[C@@H]3O[C@](C#C)(CO)[C@@H](O)C3)=NC(Cl)=N1

Molecular Formula

C13H13ClN4O3

Molecular Weight

308.72

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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