MD102
Product Specifications
CAS Number
2755794-94-4
Target
Apoptosis, Glutaminase
Related Pathways
Proteases/Proteasome, Apoptosis
Bioactivity
MD102, with an IC50 value of 0.35 μM, is a potent TG2 inhibitor that stabilizes p53 by inhibiting TG2. This results in a decrease in p-AKT and p-mTOR downstream signaling, ultimately inducing tumor cell apoptosis [1].
Smiles
O=C1C2=C(N=C(N2)C3=CC(F)=C(Br)C=C3)C(=O)C(Cl)=C1Cl
Molecular Formula
C13H4BrCl2FN2O2
Molecular Weight
389.99
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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