LMP517
Product Specifications
CAS Number
1883730-99-1
Target
Topoisomerase
Related Pathways
DNA Damage/DNA Repair
Bioactivity
LMP517 (NSC 781517), an indenoisoquinoline, is a potent dual TOP1 and TOP2 inhibitor that shows better antitumor activity than its parent compound LMP744 against H82 (Small Cell Lung Cancer) xenografts, inducing TOP1 cleavage complexes (TOP1ccs) and TOP2ccs [1].
Smiles
C(CCNCCO)N1C2=C(C=3C(C1=O)=CC(F)=CC3)C(=O)C=4C2=CC5=C(C4)OCO5
Molecular Formula
C22H19FN2O5
Molecular Weight
410.4
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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