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Leucettinib-21

Product Specifications

CAS Number

2732859-75-3

Bioactivity

Leucettinib-21 (LCTB-21) (compound 4) serves as a selective and potent inhibitor of DYRK1A, exhibiting IC50 values of 2.4, 6.7, 12, 33, and 5 nM for DYRK1A, DYRK1B, CLK1, CLK2, and CLK4, respectively. This compound is applicable for the study of Down syndrome and Alzheimer's disease [1].

Smiles

C(\C=1C=C2C(=CC1)N=CS2)=C/3\NC(N[C@H](CC(C)C)COC)=NC3=O

Molecular Formula

C18H22N4O2S

Molecular Weight

358.46

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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