Leucettinib-21
Product Specifications
CAS Number
2732859-75-3
Bioactivity
Leucettinib-21 (LCTB-21) (compound 4) serves as a selective and potent inhibitor of DYRK1A, exhibiting IC50 values of 2.4, 6.7, 12, 33, and 5 nM for DYRK1A, DYRK1B, CLK1, CLK2, and CLK4, respectively. This compound is applicable for the study of Down syndrome and Alzheimer's disease [1].
Smiles
C(\C=1C=C2C(=CC1)N=CS2)=C/3\NC(N[C@H](CC(C)C)COC)=NC3=O
Molecular Formula
C18H22N4O2S
Molecular Weight
358.46
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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