LASSBio-2052
Product Specifications
CAS Number
2549160-15-6
Target
Others, Apoptosis, DNA/RNA Synthesis
Related Pathways
Others, Cell Cycle/Checkpoint, DNA Damage/DNA Repair, Apoptosis
Bioactivity
LASSBio-2052, a derivative of N-acylhydrazone with antitumor activity against hepatocellular carcinoma (HCC), inhibits HCC cells HepG2 and Hep3B with IC50 values of 18 and 41 μM, respectively. LASSBio-2052 arrests the cell cycle at G2/M phase through downregulation of FOXM1 and induces apoptosis in HCC cells [1].
Smiles
C(NN=CC1=CC=C(C(F)(F)F)C=C1)(=O)C2=C(NCC3=CC(O)=C(OC)C=C3)C=CC=C2
Molecular Formula
C23H20F3N3O3
Molecular Weight
443.42
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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