Kartogenin sodium
Product Specifications
CAS Number
1401168-39-5
Target
TGF-beta/Smad
Related Pathways
Stem Cells
Bioactivity
Kartogenin (KGN) sodium acts as an inducer of chondrogenic tissue formation (EC 50: 100 nM) . It promotes chondrogenesis by binding to fibrin A, disrupting its interaction with the transcription factor core binding factor beta subunit (CBF?), and modulating the CBF?-RUNX1 transcriptional program. Additionally, Kartogenin sodium aids tendon-bone junction (TBJ) wound healing by stimulating collagen synthesis. It is extensively utilized in cell-free therapies for cartilage regeneration and protection, tendon-bone healing, wound healing, and limb development. The compound is also vital for cartilage repair, coordinating limb development, and osteoarthritis (OA) research [1] [2] [3] [4].
Smiles
O=C(C1=C(C=CC=C1)C([O-])=O)NC2=CC=C(C3=CC=CC=C3)C=C2.[Na+]
Molecular Formula
C20H14NNaO3
Molecular Weight
339.32
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Product Datasheet
https://www.targetmol.com/attachment/DataSheet/212216107392565399/T86778
Available Sizes
Curated Selection
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