JTE-151
Product Specifications
CAS Number
1404380-58-0
Target
ROR
Related Pathways
Metabolism
Bioactivity
JTE-151, a RORγ inhibitor, suppresses the overactive immune response by inhibiting RORγ, which is linked to the activation of Th17 cells. This action positions JTE-151 as a potential candidate for autoimmune disease research [1].
Smiles
[C@@H](CC(NC1=C(Cl)C=C(C)C=C1)=O)(CCC(O)=O)C=2C(=C(ON2)[C@H]3C[C@@H](CC(C)(C)C)C3)C4CC4
Molecular Formula
C28H37ClN2O4
Molecular Weight
501.06
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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