JAK3/BTK-IN-7
Product Specifications
CAS Number
2844387-16-0
Target
JAK, BTK
Related Pathways
Chromatin/Epigenetic, Tyrosine Kinase/Adaptors, Angiogenesis, Stem Cells, JAK/STAT signaling
Bioactivity
JAK3/BTK-IN-7 (XL-12), characterized as a JAK3/BTK inhibitor, exhibits IC 50 values of 2 nM and 14 nM for JAK3 and BTK respectively. This compound demonstrates anti-inflammatory properties and is applicable in research related to rheumatoid arthritis [1].
Smiles
NC1=C2C(=NN(C2=NC=N1)[C@H]3CN(C(C=C)=O)CCC3)C4=C5C(=C(NC(=O)C6=CC=C(N(C)C)C=C6)C=C4)OCO5
Molecular Formula
C29H30N8O4
Molecular Weight
554.6
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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