JAK1-IN-13
Product Specifications
CAS Number
2778330-90-6
Target
JAK
Related Pathways
Angiogenesis, Stem Cells, JAK/STAT signaling, Tyrosine Kinase/Adaptors, Chromatin/Epigenetic
Bioactivity
JAK1-IN-13 (compound 36b) functions as an orally active, potent, and highly selective JAK1 inhibitor, exhibiting an IC 50 of 0.044 nM. It effectively reduces STAT3 phosphorylation [1].
Smiles
N(C1=C2C(=NC=C1C(NC)=O)NC=C2)[C@@H]3C[C@H](C)N(CC4=CC=C(C(F)(F)F)C=C4)CC3
Molecular Formula
C23H26F3N5O
Molecular Weight
445.48
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
TMAB-02031B-01 100 µL
Rabbit Anti-Monkey IgG H&L Secondary Antibody-Biotin
Sign In for Pricing
View Details TMAB-02031B-02 1 mL
Rabbit Anti-Monkey IgG H&L Secondary Antibody-Biotin
Sign In for Pricing
View Details 
GTR15287931 1 Vial
Lentiviral mouse Slc1a2 shRNA (UAS) - Lentiviral mouse Slc1a2 shRNA (UAS, iRFP) (100)
Sign In for Pricing
View Details 
LV770281 1.0 µg DNA
MIR4751 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV-GFP-2A-Puro)
Sign In for Pricing
View Details