JAK1-IN-12
Product Specifications
CAS Number
2945204-95-3
Target
JAK
Related Pathways
Tyrosine Kinase/Adaptors|||Stem Cells|||Chromatin/Epigenetic|||JAK/STAT signaling|||Angiogenesis
Bioactivity
JAK1-IN-12, a selective inhibitor of JAK1, exhibits an IC50 of 0.0246 ?M and demonstrates IC50 values of 0.423 ?M, 0.410 ?M, and 1.12 ?M for JAK2, JAK3, and TYK2, respectively. It promotes hair growth in mice and is applicable for researching immune and inflammatory diseases [1].
Smiles
N([C@@H]1[C@@]2(CC3(O)C[C@@]1(CC(C2)C3)[H])[H])C=4C(=CN=C5C4C=CN5)C=6C=NNC6
Molecular Formula
C20H23N5O
Molecular Weight
349.43
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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