JAK/HDAC-IN-3
Product Specifications
CAS Number
3029138-70-0
Target
HDAC, JAK
Related Pathways
DNA Damage/DNA Repair, Stem Cells, Angiogenesis, Chromatin/Epigenetic, JAK/STAT signaling, Tyrosine Kinase/Adaptors
Bioactivity
JAK/HDAC-IN-3 (13a), a dual inhibitor of JAK and HDAC, exhibits IC50 values of 25.36 nM for JAK2, 0.2 μM for HDAC, and 0.43 μM for HDAC1, respectively [1].
Smiles
N(C1=NC(NC2=CC(F)=C(OCCCCCCC(NO)=O)C=C2)=NC=C1C)C3=CC(S(NC(C)(C)C)(=O)=O)=CC=C3
Molecular Formula
C28H37FN6O5S
Molecular Weight
588.69
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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