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IR-58

Product Specifications

CAS Number

2374274-85-6

Target

Others, Apoptosis, Autophagy

Related Pathways

Others, Apoptosis, Autophagy

Bioactivity

IR-58 is a mitochondria-targeting near-infrared (NIR) fluorophore that serves as an autophagy enhancer. It eliminates tumor cells and triggers apoptosis by promoting excessive autophagy through the reactive oxygen species (ROS) -Akt-mTOR pathway [1].

Smiles

C(CCCCCCCCCC(NCC(OC)=O)=O)N1C=2C(C(C)(C)C1=CC=C3C(Cl)=C(C=CC4=[N+](CCCCCCCCCCC(NCC(OC)=O)=O)C=5C(C4(C)C)=CC=CC5)CCC3)=CC=CC2.[Br-]

Molecular Formula

C58H82BrClN4O6

Molecular Weight

1046.65

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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