IR-58
Product Specifications
CAS Number
2374274-85-6
Target
Others, Apoptosis, Autophagy
Related Pathways
Others, Apoptosis, Autophagy
Bioactivity
IR-58 is a mitochondria-targeting near-infrared (NIR) fluorophore that serves as an autophagy enhancer. It eliminates tumor cells and triggers apoptosis by promoting excessive autophagy through the reactive oxygen species (ROS) -Akt-mTOR pathway [1].
Smiles
C(CCCCCCCCCC(NCC(OC)=O)=O)N1C=2C(C(C)(C)C1=CC=C3C(Cl)=C(C=CC4=[N+](CCCCCCCCCCC(NCC(OC)=O)=O)C=5C(C4(C)C)=CC=CC5)CCC3)=CC=CC2.[Br-]
Molecular Formula
C58H82BrClN4O6
Molecular Weight
1046.65
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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