INX-315
Product Specifications
CAS Number
2745060-92-6
Target
CDK, Early 2 Factor (E2F)
Related Pathways
Cell Cycle/Checkpoint
Purity
0.9988
Bioactivity
INX-315 is an orally active, selective CDK2 inhibitor that induces cell cycle arrest and senescence in solid tumours, suppresses E2F target gene expression, and exhibits anticancer activity in ccne1-amplified cancers and cdk4/6i-resistant intraductal breast cancer models.
Smiles
O=C1NNC2=CC=3C=NC(=NC3N2C14CCCCC4)NC5=CC=C(C=C5)S(=O)(=O)N
Molecular Formula
C19H21N7O3S
Molecular Weight
427.48
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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