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IKZF1-degrader-1

Product Specifications

CAS Number

2915586-02-4

Target

IKZF, Molecular Glues

Related Pathways

Immunology/Inflammation, PROTAC

Bioactivity

IKZF1-degrader-1 (Compound 9-B) serves as a potent degrader of the IKZF1 protein, exhibiting a DC50 of 0.134 nM. It is applicable in the degradation of tumors [1].

Smiles

C(C=1C=2C=3C(N(C(=O)C3C=C(F)C2)[C@@H]4C(=O)NC(=O)CC4)=CC1)C5=CC=C(CN6CCN(CC6)C7=C(F)C=C(C#N)C=C7)C=C5

Molecular Formula

C35H29F2N5O3

Molecular Weight

605.63

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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