IDOR-1117-2520
Product Specifications
CAS Number
2737274-49-4
Target
CCR
Related Pathways
Immunology/Inflammation, GPCR/G Protein, Microbiology/Virology
Bioactivity
IDOR-1117-2520 is a highly potent and selective antagonist of CCR6, effectively impeding CCL20-mediated calcium flow with an IC50 of 63 nM and inhibiting β-arrestin recruitment to human CCR6 with an IC50 of 30 nM in cells expressing recombinant human CCR6. This compound is suitable for researching autoimmune diseases [1].
Smiles
[C@](O)([C@]1(C)CN(C)C1)(C=2C=C(C=NC2)C=3N=C(C(C)(C)O)ON3)C4=CC=C(C(C)C)C=C4
Molecular Formula
C25H32N4O3
Molecular Weight
436.55
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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