HSD17B13-IN-99
Product Specifications
CAS Number
2849338-46-9
Target
Dehydrogenase
Related Pathways
Metabolism
Bioactivity
HSD17B13-IN-99 (Compound 6) serves as an inhibitor targeting hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), demonstrating an IC50 value of <0.1 μM for estradiol. This compound is utilized in the study of liver, metabolic, and cardiovascular diseases, including NAFLD, NASH, and drug-induced liver injury (DILI) [1].
Smiles
N(C(=O)C=1N=C(C(F)(F)F)C(O)=CC1)C2=C3C(N=CN(CCC4=C(OC)C=CC=C4)C3=O)=CC=C2
Molecular Formula
C24H19F3N4O4
Molecular Weight
484.43
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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