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HSD17B13-IN-97

Product Specifications

CAS Number

2849338-44-7

Target

Dehydrogenase

Related Pathways

Metabolism

Bioactivity

HSD17B13-IN-97 (compound 4) is an effective inhibitor of hydroxysteroid 17ß-dehydrogenase 13 (HSD17B13), demonstrating an IC 50 value of ≤0.1 μM. This compound shows promise for studying Nonalcoholic fatty liver diseases (NAFLDs), nonalcoholic steatohepatitis (NASH), or drug-induced liver injury (DILI) [1].

Smiles

N(C(=O)C=1N=C(C(F)(F)F)C(O)=CC1)C2=C3C(N=CN(CC4=C(F)C=CC=C4)C3=O)=CC=C2

Molecular Formula

C22H14F4N4O3

Molecular Weight

458.37

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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