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HSD17B13-IN-93

Product Specifications

CAS Number

2848620-87-9

Target

Dehydrogenase

Related Pathways

Metabolism

Bioactivity

HSD17B13-IN-93 (Compound 9) acts as an inhibitor targeting hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), exhibiting an IC 50 for estradiol ranging between greater than 0.1 μM and up to 0.5 μM. Its application extends to the study of liver, metabolic, and cardiovascular diseases including NAFLD and NASH, alongside drug-induced liver injury (DILI) [1].

Smiles

C(NCC1=C(C(F)(F)F)C=CC=C1)(=O)C2=C(NC(=O)C3=CC(Cl)=C(O)C(F)=C3)N=CS2

Molecular Formula

C19H12ClF4N3O3S

Molecular Weight

473.83

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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