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HSD17B13-IN-91

Product Specifications

CAS Number

2848620-83-5

Target

Dehydrogenase

Related Pathways

Metabolism

Bioactivity

HSD17B13-IN-91 (Compound 5), an inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), exhibits an IC50 value for estradiol ranging from greater than 0.1 μM to 0.5 μM or less. This compound is applicable in the study of liver, metabolic, and cardiovascular diseases including NAFLD and NASH, and drug-induced liver injury (DILI) [1].

Smiles

N(C(=O)C1=CC(Cl)=C(O)C=C1)C2=C(C(NCCC(C)(C)C)=O)C(C)=NS2

Molecular Formula

C18H22ClN3O3S

Molecular Weight

395.9

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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