HSD17B13-IN-86
Product Specifications
CAS Number
2770247-78-2
Target
Dehydrogenase
Related Pathways
Metabolism
Bioactivity
Compound 188 (HSD17B13-IN-86) serves as an inhibitor targeting hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), demonstrating potency with an IC50 value of ≤ 0.1 μM against estradiol. This compound is applicable in the study of various conditions including liver, metabolic, and cardiovascular diseases, specifically NAFLD, NASH, and drug-induced liver injury (DILI) [1].
Smiles
C(NC(=O)C1=C(NC(=O)C2=CC(Cl)=C(O)C(Cl)=C2)SC=N1)C=3C=4C(N(C)N3)=CC=CC4
Molecular Formula
C20H15Cl2N5O3S
Molecular Weight
476.34
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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