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HSD17B13-IN-85

Product Specifications

CAS Number

2770247-76-0

Target

Dehydrogenase

Related Pathways

Metabolism

Bioactivity

HSD17B13-IN-85 (186) serves as an inhibitor of 17β-Hydroxysteroid dehydrogenases (HSD17B13), exhibiting potent activity with an IC 50 of less than 0.1 μM for Estradiol. It is primarily utilized in the study of NAFLD (Nonalcoholic fatty liver diseases) [1].

Smiles

N(C(=O)C1=CC(Cl)=C(O)C(Cl)=C1)C2=C3C(N=C(CF)N(CC4=C(C(F)(F)F)C=CC=C4)C3=O)=C(C)C=C2

Molecular Formula

C25H17Cl2F4N3O3

Molecular Weight

554.32

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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