HSD17B13-IN-83
Product Specifications
CAS Number
2770247-41-9
Target
Dehydrogenase
Related Pathways
Metabolism
Bioactivity
HSD17B13-IN-83 (Compound 150), an inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), exhibits strong inhibitory activity with an IC50 of ≤ 0.1 μM against estradiol. This compound is applicable in the research of various diseases, including liver diseases, metabolic disorders, and cardiovascular conditions, specifically NAFLD or NASH, and drug-induced liver injury (DILI) [1].
Smiles
N(C(=O)C1=CC(Cl)=C(O)C(Cl)=N1)C2=C3C(N=C(C)N(CC4=C(OC(F)(F)F)C=CC=C4)C3=O)=C(F)C=C2
Molecular Formula
C23H14Cl2F4N4O4
Molecular Weight
557.28
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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